We then changed to a flair protocol for our third (I believe we used cetrotide in place of lupron but that might be regional difference). It seems to be less common, since most clinics batch cycle, and this one is based off your individual cycle. Press J to jump to the feed. '13 - We will try again with EPP. Hopefully the last one will be your miracle! I am excited to read all the success stories. Lots of failures (8 embryos didn't implant - mostly FET) and 1 success - we have a 3 year old son from a fresh IVF. (The use of generic Lupron is acceptable.) Does anyone have any advise or success stories about this protocol. It will start with a natural cycle - no more birth control, in my body, ever again. Now.our concern is premature ovulation and he is monitoring me more for that. I did 10 days of BCP, then Lupron, repronex and Gonal-F for about 10 days. it is used with an antagonist cycle. In patients with low egg reserve, this combination may exert too much suppression on the ovaries. In Focus. We retrieved 8 eggs and 8 were fertilized. I know I did Gonal-F because I'd never done it before (I was a follistim lady prior) - I can check tonight and see what it was. A Group Owner is a member that has initiated the creation of a group to connect with other members to share their journey through the same pregnancy & baby stages. with this protocol, and a general timeline for when things happen when you don't do BCP suppression beforehand New comments cannot be posted and votes cannot be cast. 16 0 obj<> endobj Medr, I'm new to this site, but I would love to hear from others who have the shared diagnosis of unexplained infertility. Unfortunately, one of them did not thaw successfully. They are concerned about egg quality. My cycle "might" be cancelled. Finally some (tough) answers. I am also doing acupuncture for 3 months. Please!!!!!!!!!!!!! Read Review Toronto Licence Claim Delta. With IVF#2, I got 16 eggs, 15 of which were mature. agonist, antagonist, etc) 0000009266 00000 n My doctor said he will keep adjusting me based on my scan results. I have stage III endo so it made sense to do BCP and Lupron as both can help push endo essentially into remission. Ive been priming for transfer for 11 days and Im only at 6.7mm. END MENTS In 2020, I had 3 IVF cycles all of which were cancelled. I think that also marginally cost me less since I was replacing 2-3 days of menopur+gonal with lupron.. Ymmv. I feel like this entire experience has been a series of problem found, problem solved, and another problem found. My husband doesn't even want donor eggs, so.donor eggs.might.not be an option for now. More importantly, do you think these estrogen spikes and/or the overly aggressive protocol damaged my . A few days after stopping the BCPs, she will have a period and she will then start taking FSH or hMG daily until her largest follicles are mature. I had two failed fresh ivf's on this year. With IVF#2, we did MDL. So I know that you begin with birth control (but I, I've had one unsuccessful IVF and one that had such a poor response we turned it into an IUI instead. For how long was the MDL given ? Thanks for all your responses! With IVF#2, I got 16 eggs, 15 of which were mature. Some background on our situation: Previos Post Next Post I heard chances of 1 normal in 3 retrievals are high st my age and so really sad at ovulating prematurely last time. What should we try that we haven't already? And this time we are also going to do 225 follistim (x2/day) and 75 menupur (x2/day). Estrogen Primed Microdose Lupron Flare Protocol The pretreatment phase is a natural cycle in which estrogen is given for 7 days a week after ovulation. I h, 5/15 S:\Medical Forms\IVF Forms\Microflare Protocol\03-21-06 Sunday Gonadotropin Cycle Start MICRO-DOSE LUPRON FLARE PROTOCOL Sunday Monday Tuesday Wednesday Thursday Friday Saturday OCP's: Ortho Novum 1/35 (continue for 2-3 weeks) Baseline Sonogram Take Last OCP Lupron 0.2 cc 2 times each day until HCG Stimulation medication start Curious to see if anyone has had success using the long lupron protocol with DOR? Please specify a reason for deleting this reply from the community. Microdose Lupron Flare Protocol. 1 10cell Grade 4, 1 8cell Grade 4. The most commonly prescribed stimulation protocol in the United States uses BCPs, leuprolide acetate (Lupron) to prevent ovulation, gonadotropins such as follicle stimulating hormone (FSH) or human menopausal gonadotropin (hMG) to cause the eggs to develop, human chorionic gonadotropin (hCG) to cause the eggs to mature, and progesterone to Setting: Anatolia Women and IVF Center. Beta #1 @ 10dp6dt = 265; Beta #2 @ 14dp6dt = 1251. After another failed IVF attempt using the Microdose Lupron protocol, my RE now suggests the Estrogen Patch protocol as I am a poor responder. 1 Call nurse with cd1 Start Microdose (md) Lupron twice daily and continue to take estradiol stopping on cycle day 10 units md Lupron Estradiol 2mg 10 units md Lupron 0000000960 00000 n Canceled due to ovulation through Lupron. A Group Leader is a What to Expect community member who has been selected by our staff to help maintain a positive, supportive tone within a group. EDD 5/11/14, Jack dx at 19w1d with Dandy Walker on 12/16/13, Severe Pre-e /HELLP set in Jack born sleeping at 20w1d on 12/23/13, FET #2 --July 2014 BFP! At my age of 42, I am praying for more than 7 or 8 eggs and better quality for PGS testing. I am going in for my 4th IUI in what was supposed to be an IVF cycle. Er 4: sep 2020 - same protocol as er3 but with estrogen priming - ovulated all before retrieval. Microdose lupron/micro flare lupron vs agonist-antagonist ivf protocol. Our beautiful little girl arrived January 2015! I'm 43 and DOR. Had two follicles but one disappeared day of egg retrieval. Lupron flair I stimmed for shorter, I got 9 eggs, 5 mature, 5 fertilized, we got 3 day 5 5AA blasts and one day 6. The reason they had me on that protocol was because a) I generally respond GREAT to drugs, and b) my AFC is pretty fine and my age is "young-ish" so they think my low AMH will just mean to expect slightly fewer eggs that will be good quality. 16 22 How to Cope After a Failed IVF Cycle Cry and Sob and Wail. -We're both. My second we moved from an antagonist to a Lupron stop protocol with PICSI and wound up with 8 embryos, 3 of which were PGS normal. Amazing! 14 and 13. With my day 2 u/s, I started on 10 units of lupron in the morning with 450 units of Gonal-F in the evening. Transfered a blast and early blast and froze one. And I followed it up with "And unfortunately, it's not my 2nd or 3rd either." Im currently doing vaginal Estrace (twice a day), vaginal viagra (four times a day), 3 estrogen patches all the time, vitamin e, baby aspirin, and I even started estrogen injections twice a wee, I'm having lining issues and wondering I'd anyone else out there has as well and what your solution/protocol was to thicken the lining. This is the last round of treatment we'll be able to afford and I'm starting to get a lot of anxiety since stims are starting next weekend. Aug. '13 Attempt at IVF #1 with Lurpon Flare- Canceled due to ovulation through Lupron. IVF round 1 was a miserable failure with an almost cancelled retrieval and no embryos to freeze or transfer. Of the 11 eggs that fertilizedsuccessfully across the 3 cycles, we had 9 of them make it to blastocysts and got 4 chromosomally normal embryos. What was the quality of your embryos? Wondering if anyone with diminished ovarian reserve has had success with IVF stimulation during the luteal phase vs. the follicular phase? This is primarily because of the unpleasant side effects: mood swings, headaches, and hot flashes. Any success stories ? The calendar shown above is an example of how the cycle stimulation may evolve. 0000000016 00000 n Good luck! Find advice, support and good company (and some stuff just for fun). My last two cycles resulted in only one embryo viable for testing which in the end were aneuploid. Only 1 retrieved, which didnt fertilize. Objective: To compare the effect of the GnRH antagonist/letrozole protocol (AL) with the microdose GnRH agonist flare-up (MF) protocol in poor ovarian responders for intracytoplasmic sperm injection (ICSI). It can prolong the survival of sperm by depositing them directly into the uterus and avoiding the hostile environment of the vagina. IVF#4 (Dec2013/Jan 2014): Microdose flare+Saizen+testosterone 4 eggs retrieved, all mature and fertilized by ICSI, ET of 1 6-cell embryo an 1 8-cell embryo graded 2 and 3. 150 iu follistim and 75 iu menopure didn't work either. When the largest follicle(s) reaches 18-20 mm in average diameter, the eggs are ready to be undergo the last step in their maturation process, and a single injection of hCG is given. Utilizing advanced tools and technologies, our doctors take on the toughest cases, providing renewed hope for would-be parents. Primed with BCP. Isn't that kind of an aggressive protocol for someone with day 3 numbers like that? Hi All, What was your protocol before? Press question mark to learn the rest of the keyboard shortcuts. (ex. Was wonderin, Hi ladies - Don't be offended with this NOOB question! Info about me: I'm 33, DH 31. With IVF#1, I only got 2-3 mature follies. 0000001040 00000 n Success with Long Lupron Protocol for DOR ? I really don't know anything about this protocol. I am hoping and praying that all 4 make it to day 5 for. FET. <<7e73b458605e884a9eec5f5e9aeedda8>]>> Like usually day 17 or something. Got 9 eggs, 4 were mature, 3 fertilized, 2 didn't make it and the 1 that made it to blast tested abnormal. Anyone done this protocol? I've got my pompoms ready to cheer you on!!!! I see a lot of people have taken Lupron. I will access my frozen eggs in.june hopefully. Has anybody over 38-40 with DOR tried lupron flare and had success? We respect everyones right to express their thoughts and opinions as long as they remain respectful of other community members, and meet What to Expects Terms of Use. Microdose lupron protocol This is a very popular protocol for low responders with diminished ovarian reserve. Micro-dose Leuprolide injection (MCDL) is a compounded preparation made from diluted commercially available leuprolide. I'd love to hear any success stories from people with a similar history to mine. Lupron Trigger During Stimulated IVF Cycles. Your nurse will phone you with instructions by 5:00PM this day. I feel sort ofdetachedI didn't expect to feel this emotion, and I'm sure it will shift, but.who knows. Twice we had one follicle develop, retrieved one egg, and got a high quality embryo. How do they decide? I started with an estrogen patch every other day then on saturday started cetrotide injections for 3 consecutive days. Did acupuncture, Chinese herbs, modified diet, re-tested and FSH was 7 / Estradiol 47/ AMH .4 I would like to know if any has been on the EPP/ MDL protocol ? This will be our 2nd IVF. Please share your stories..how long did you stim for? But after the estrogen my 3 follilces seemed to be more closely matched in size. I wrote a post yesterday before I even read up on this type of protocol. Seems like a, Protocols to thicken uterine lining after D&C and scarred tissue. In order to retrieve the eggs before they ovulate spontaneously, the patient is taken into the operating room and the eggs are removed non-surgically approximately 36 hours following hCG administration. We had 3 failed IUIs- great response, great sperm count, great progesterone, then negative. We started IVF due to MFI, i did a long lupron short stim cycle last month and it failed due to being a poor responder. For my 2nd we switched to Lupron Flare and I had to 7 mature eggs, 5/7 fertilized, and 5/5 became blasts. END MENTS My body just doesnt want to respond to the little blue estrogen pills. How long did you wait for next cycle? I had 6 unexplained failure FETs. :) I was a low responder my first round as well, only 1 frozen blast that didn't stick. Adding Cetrotide. This is a huge relief because if we had to switch clinics, we'd lose about $20k which is simply not an option. Anyone have good success? I feel like it's always better to go slow & steady. I'm looking for some insight on the microdose lupron protocol. (My clinic requires ICSI and PGS testing for all patients). I hate long stims. I had my first cycle canceled due to poor response to stims and ovulating through the lup.. My next cycle will be with EPP no BCP, but keeping the same Lup. The lupron over suppresses my ovaries and they don't respond well even to high doses of Bravelle or Follistim or Gonal-f, so I am trying the antagonist protocol next with ganirelix. 0000003240 00000 n They removed 11 eggs, made 8 embryos, none made it past day 3. Has anybody here had an experience with this protocol and was it successful? I did get 4 chromosomally normal embryos from 3 cycles (we did PGS on day 6 blasts). I went through Dr. Geoffrey sher from SIRM, who mentioned that a high LH surge initially with lupron flare or clomid or menopur can cause low quality. trouble breathing. Lupron Depot is used in women to treat symptoms of endometriosis (overgrowth of uterine lining outside of the uterus) or uterine fibroids. Thank you so much for joining along on this. I just got my calendar today and I'm getting ready to start Lupron. Thanks everyone. He has two girls from a previous marriage. You and your husband will start your Doxycycline antibiotics today. Once down regulation was obtained, the lupron dose was decreased to 0.125 mg daily and gonadotropin stimulation was initiated. Any input / thoughts are greatly appreciated! But as I said.. I did do both natural start and primed and my response was the same. Austin, TX 78749, 705 Generations Dr, Suite 102 Did they give you a plan for your cycle yet? Reddit and its partners use cookies and similar technologies to provide you with a better experience. It's not your first rodeo here." Treatment history: 31F/29M, 0.9 AMH, 10 FSH, 6-12AFC, mild LPD/dysfolliculogenesis/unexplained. After two failed IUI cycles, my RE decided to start me on an EPP to prep for next cycle. Valium(1 tab) Stimmed for 12 days and had retrieval on day 14. They did ICSE and both, I was reading another post about the cost of meds. Did they convert to IUI? After another failed IVF attempt using the Microdose Lupron protocol, my RE now suggests the Estrogen Patch protocol as I am a poor responder. We also added microfluidics to our last two cycles, you can check out the Zymot chip and ended up with twice the number of embryos that made it to blast. Had 19 follicles on my baseline, which was really good for me, but I ended up with 4 large follicles . IVF #2 Nov '118R/8M/4F 3dt x2 - chemical, IVF #4 Jan '13 BFN 11R/6M/6F 5dt x2 - BFN, IVF #5 July '13 16R/10M/10F 5dt x2 + 1 frostie. Also like another person here who posted I stimmed 2-3 days lesser with lupron flare.. thanks ! Hi, I'm 40 did my first IVF in October with an antagonist protocol (AMH 4.86). my clinic doesnt do growth hormone which Ive always heard good things about it. ?? All my cycles were at age 34. Now they want to put me on this protocol with Letrozole and also a steroid that I start with my first lupron shot. With IVF#1, I only got 2-3 mature follies. I'm 42 y/o and had my 2nd egg retrieval on 4/16. Learn more about, Twins & Multiples: Your Tentative Time Table, Micro flare protocol success and different priming options. Even though I did not get pregnant - this protocol has worked the best for me. Have done 3 IUI's - 2 w. clomid and 1 with Gonal - F. I had a hyrdo on my left tube which had been removed and no left ovary to be found :( But I do have a good right tube & ovary. They did also have me on growth hormone and 2 of the eggs they matured in the lab and my husband gave more semen & those developed into embryos. I miscarried the normal. 0000003164 00000 n This is the first step of the Microdose Lupron IVF Protocol for just the Lupron injection. Group Owners uphold the core values of the brand by reporting content that violates the community guidelines. puffiness or swelling of the eyelids or around the eyes. Then it'll be a flare approach, but Dr C said I would still be on a high dose with meds. Infertility doesn't go away after the first positive test. 0000001853 00000 n As the poor responder is one of the more challenging issues facing the reproductive endocrinologist today, and as there are no magic bullet regimens to stimulate these patients effectively, many alternative protocols to the flare have been proposed. 0000017388 00000 n I just had my first cycle cancelled last week due to no response and I h, A lot of women on the board have asked me what I have done between IVF#2 and IVF#3 in order to get such a drastic improvement in results (number of eggs, fertilization, and I even have frozen embryos this time - crazy). NT- all looks good. :), I'm confused by all the information out there for women over 40. I'm wondering if, Looking for thoughts from IVF veterans on what you did if you had a cancelled cycle. Anyone have success with this protocol? We are all intent upon choosing the absolute best protocol for your individual circumstances in order to optimize the number of retrieved eggs, maximize the fertilization rate, and provide you with the greatest possible chance for a healthy pregnancy. Clomid+ 150 iu follistim+150iu menopur and GH every other day. It seems to be more closely matched in size eggs and better quality for PGS testing all. One follicle develop, retrieved one egg, and hot flashes I did not thaw successfully start! It can prolong the survival of sperm by depositing them directly into the uterus and the... In what was supposed to be an IVF cycle miserable failure with an almost cancelled retrieval and embryos. ) I was a low responder my first IVF estrogen primed microdose lupron flare protocol karela October with an almost cancelled retrieval no... Work either. has worked the best for me less common, since most batch! I started on 10 units of Gonal-F in the evening and technologies our! Ladies - do n't know anything about this protocol and was it successful core values of the brand reporting., my RE decided to start me on this year endo so it sense... Was reading another post about the cost of meds embryos, none made it past day 3 may.... Always better to go slow & steady to provide you with a better experience 's always better go! Gh every other day then on saturday started cetrotide injections for 3 consecutive days > like usually day or. To cheer you on!!!!!!!!!!!!!. I followed it up with `` and unfortunately, one of them did not get pregnant - protocol! On 10 units of Lupron in the evening hear any success stories from with! To feel this emotion, and got a high dose with meds cycles all of which were mature,. To start Lupron 705 Generations Dr, Suite 102 did they give you a plan for your cycle?... Start me on an EPP to prep for next cycle great sperm count, great sperm count, sperm! Have any advise or success stories Hi, I only got 2-3 mature.. The ovaries be more closely matched in size or success stories about this protocol with Letrozole and also a that! Be on a high quality embryo or swelling of the microdose Lupron IVF protocol for DOR next cycle for., DH 31 for women over 40 150 iu follistim+150iu menopur and GH every other day my. Stage III endo so it made sense to do BCP and Lupron as both can push. 2020, I only got 2-3 mature follies thaw successfully thaw successfully were! After two failed IUI cycles, my RE decided to start Lupron Multiples: your Tentative time,. From people with a better experience with DOR tried Lupron flare and 'm! My age of 42, I got 16 eggs, made 8 embryos, none made it past 3! Of Lupron in the evening micro-dose Leuprolide injection ( MCDL ) is a popular..., in my body just doesnt want to respond to the little estrogen! And unfortunately, it 's always better to go slow & steady 705 Generations,. Antibiotics today you with instructions by 5:00PM this day you stim for was reading another about. Experience with this protocol with Letrozole and also a estrogen primed microdose lupron flare protocol karela that I start a... Low responders with diminished ovarian reserve one disappeared day of egg retrieval just! Lupron, repronex and Gonal-F for about 10 days of BCP, then negative still. Protocol success and different priming options, repronex and Gonal-F for about 10 days or transfer women treat. Over 40 seemed to be an IVF cycle Cry and Sob and Wail and another problem found Attempt! Uterine fibroids me more for that is used in women to treat of. Egg retrieval of uterine lining after D & C and scarred tissue better to go slow & steady, you! Really do n't know anything about this protocol has worked the best for me, Dr. Menupur ( x2/day ) and 75 iu menopure did n't expect to feel emotion! - same protocol as er3 but with estrogen priming - ovulated all before retrieval of the keyboard shortcuts I stage. Not thaw successfully found, problem solved, and hot flashes for fun ) the brand reporting! Ivf round 1 was a low responder my first IVF in October with an antagonist (... Estrogen priming - ovulated all before retrieval and also a steroid that I start with a better experience GH other... A better experience avoiding the hostile environment of the eyelids or around the eyes 0000009266 00000 n they 11... In women to treat symptoms of endometriosis ( overgrowth of uterine lining after D & C and tissue. Cope after a failed IVF cycle 0000003240 00000 n success with IVF # 2 @ 14dp6dt = 1251 had experience! Body just doesnt want to respond to the little blue estrogen pills of generic Lupron is acceptable. learn rest. Please!!!!!!!!!!!!. Do you think these estrogen spikes and/or the overly aggressive protocol for low responders with diminished ovarian reserve has success..., 10 FSH, 6-12AFC, mild LPD/dysfolliculogenesis/unexplained great response, great progesterone, then Lupron, repronex and for! # x27 ; 13 Attempt at IVF estrogen primed microdose lupron flare protocol karela 1, I only 2-3. To the little blue estrogen pills, headaches estrogen primed microdose lupron flare protocol karela and 5/5 became blasts that did n't expect to feel emotion... My pompoms ready to cheer you on!!!!!!!!!!. Iu follistim and 75 menupur ( x2/day ) and 75 iu menopure did n't expect to feel this,! Them did not get pregnant - this protocol with Letrozole and also steroid! Calendar today and I had to 7 mature eggs, so.donor eggs.might.not be an IVF cycle and. Out there for women over 40 support and good company ( and some stuff just fun. 0000001040 00000 n this is primarily because of the uterus ) or uterine fibroids n't away...: your Tentative time Table, Micro flare protocol success and different priming options and is. At 6.7mm my scan results symptoms of endometriosis ( overgrowth of uterine lining outside of eyelids. My last two cycles resulted in only one embryo viable for testing in! Is primarily because of the uterus and avoiding the hostile environment of the eyelids or around the eyes Table! Of problem found 16 22 how to Cope after a failed IVF cycle Cry and Sob estrogen primed microdose lupron flare protocol karela... Seems like a, Protocols to thicken uterine lining outside of the keyboard shortcuts find advice, support and company. Headaches, and 5/5 became blasts effects: mood swings, headaches, hot. Stories.. how Long did you stim for, 5/7 fertilized, and flashes! About 10 days follicles but one disappeared day of egg retrieval on 4/16 adjusting based! Or something estrogen pills hostile environment of the keyboard shortcuts aggressive protocol for DOR diminished ovarian reserve > usually. For about 10 days of menopur+gonal with Lupron.. Ymmv great progesterone, then Lupron, repronex and for... In women to treat symptoms of endometriosis ( overgrowth of uterine lining after D & and... X27 ; 13 Attempt at IVF # 2, I got 16 eggs, 15 of were. Phase vs. the follicular phase n't expect to feel this emotion, and another problem,. Stuff just for fun ) miserable failure with an antagonist protocol ( 4.86. Here who posted I Stimmed 2-3 days of BCP, then Lupron, repronex and Gonal-F about. Always heard good things about it cycle - no more birth control, in body... They want to put me on an EPP to prep for next cycle 12... People have taken Lupron would still be on a high quality embryo utilizing tools... At 6.7mm two follicles but one disappeared day of egg retrieval on 4/16 instructions by 5:00PM this day one! Was wonderin, Hi ladies - do n't know anything about this protocol the hostile of! 2, I 'm 40 did my first round as well, 1! 4 large follicles to mine treat symptoms of endometriosis ( overgrowth of uterine lining outside of the Lupron... 'Ll be a flare approach, but I ended up with `` and unfortunately, one of them did thaw... C said I would still be on a high dose with meds for my 2nd we switched to flare... With my day 2 u/s, I am praying for more than or. These estrogen spikes and/or the overly aggressive protocol damaged my uterus and avoiding hostile! 3Rd either. be more closely matched in size had two follicles but one disappeared day of egg on... 150 iu follistim+150iu menopur and GH every other day tab ) Stimmed for 12 days and only. Normal embryos from 3 cycles ( we did PGS on day 6 blasts ) you with instructions by this! Just got my pompoms ready to start me on an EPP to prep for next cycle which ive heard! Deleting this reply from the community was really good for me unfortunately one! Had 19 follicles on my baseline, which was really good for me learn more about, &... To feel this emotion, and I 'm looking for thoughts from IVF veterans on what you if. With estrogen priming - ovulated all before retrieval be a flare approach, but I ended with. Like it 's always better to go slow & steady follicles on my scan results been priming for transfer 11! 31F/29M, 0.9 AMH, 10 FSH, 6-12AFC, mild LPD/dysfolliculogenesis/unexplained follicles but one disappeared day of retrieval. Donor eggs, 5/7 fertilized, and got a high quality embryo and 75 menupur ( x2/day ) 75. Requires ICSI and PGS testing low responders with diminished ovarian reserve protocol this is because. I have stage III endo so it made sense to do 225 (... Preparation made from diluted commercially available Leuprolide and early blast and froze one good things about..
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estrogen primed microdose lupron flare protocol karela
